ChemDraw® and ChemOffice® 18



The latest release of PerkinElmer’s scientific productivity suite serves researchers, students and faculty better than ever before! ChemDraw® and ChemOffice® 18 helps you draw molecules and reactions faster than before. Hotkeys and reaction shortcut enhancements will improve your user experience with ChemDraw by cutting down drastically the amount of time needed to draw complex molecules and reactions to a sequence of key strokes. It is also now possible to switch between the different tools without relying on timeconsuming back and forth movements with the mouse. With the new hotkey enhancements you will spend far less time on drawing your reactions and much more time focusing on your research. Plus, we are adding to our bundle options to give you the broader set of scientific tools you need to do your research, from 3D modelling to spectroscopic analysis, to access to a brand new, web based Electronic Lab Notebook and scientific documentation and collaboration platform. Chemists and biologists around the world use the industry leading ChemDraw software suite to visualize and analyse their data, and for effortless creation of publication-ready, scientifically intelligent chemical drawings.

  • Dramatically reduce the time needed to draw your molecules and chemical reactions.
  • Create publication-ready chemical drawings effortlessly.
  • Smartly designed hotkeys and support for Hierarchical Editing Language for Macromolecules (HELM).
  • New reaction shortcut allows you to draw a sequence of reactions in no time, extending automatically the length and width of the page as you draw.

Short introduction video - What is ChemDraw >

chemoffice pro 150x150ChemOffice Professional

The only Research Suite you’ll need. From drawing reactions, to processing instrument data, to structuring experimental data, ChemOffice Professional has you covered. Learn more

The most robust, scientifically-intelligent research productivity suite in the world. It builds on the foundations of ChemDraw Professional, and adds access to a broad set of powerful scientific tools* to enable scientific research. Browse within ChemDraw across more than 10 M commercially available compounds by structure, or CAS RN with ChemACX Explorer. Document, search and share your research using Signals Notebook Individual Edition, a modern, web-based scientific collaboration platform. Load and process 1D NMR and LC/GC/MS data directly on your desktop with MNova CD-Edition. Get access to, and edit, your CD-files from any device with ChemDraw Cloud. Enhanced structural prediction with your favorite third party applications and Chem3D Ultra. A full suite of scientific productivity tool helping chemists and biologists alike efficiently keep track of their work, visualize and gain a deeper understanding of their results.

ChemDraw Pro product image 150x150ChemDraw Professional

Take your chemical drawing experience to the next level, enhanced with even more time-saving chemical intelligence, publication-worthy graphical templates and scientific tools. Learn more

Takes chemical drawing to the next level, with all the features in ChemDraw Prime plus: SciFinder® by CAS and Elsevier® Reaxys® integration, ChemACX Explorer add-in, 1H and 13C NMR prediction, BioDraw, Name to Structure and Structure to Name, HELM toolbar, and access to CD-Cloud.

ChemDraw Prime Product Image 150x150ChemDraw Prime

Your basic yet powerful chemical drawing tool, with all the beloved time-saving tricks and shortcuts that make ChemDraw the preferred tool for chemists since 1985. Learn more

The complete entry-level structure drawing program, with all the tools you need to quickly create chemically intelligent, publication-ready chemical structures and reactions, laboratory notes and experiment write-ups. Beyond a full set of chemical structure essentials (e.g. rings, bonds, chains, atoms and functional groups), ChemDraw Prime includes new hotkeys for drawing even faster than ever before, property calculators, chemical and lab equipment templates and handy TLC Plate drawing tools.

ChemDraw JavaScript Product Image 150x150ChemDraw JS

ChemDraw everywhere! ChemDraw JS is a web version of ChemDraw, ready to be embedded into your web application to make them "ChemDraw Smart". Learn more

Modularized ChemDraw functionality for the web! Built on JavaScript and HTML5, ChemDraw JS can be plugged into web browsers and internal applications that need to be chemicalized. Inside its lightweight packages, ChemDraw JS carries the core functionality of the CD-family including: your favorite drawing capabilities, advanced Name to Structure, Structure to Name, Hotkeys/Shortcuts, Structure Templates and Structure Query Tools. ChemDraw JS is used within CD-Cloud, Signals Notebook Individual Edition, Lead Discovery, Elsevier® Reaxys®, and PerkinElmer Signals Lead Discovery to provide a seamless web-based chemical drawing experience. Now you can use it within your own environment too.

SignalsNotebook 150x150Signal Notebook (ELN -Electronic Lab Notebook)

PerkinElmer Signals™ Notebook is a powerful new web based Electronic Lab Notebook, enabling users to instantly author and manage notebooks & experiments, facilitating Scientific Collaboration. Learn more

PerkinElmer Signals Notebook allows you to achieve meaningful scientific breakthroughs – faster, smarter and easier to keep track of your material evidence. Signals Notebook provides you with an effective scientific research data management solution, where you can write up your research data in notebooks and experiments, drag & drop, store, organize, share, find and filter data with chemical ease.


Download demo of ChemDraw 18

Contact us for a fully functional 30 days demo-edition of ChemDraw 18.


System requirements

  • Windows 7, 8 and 10 (32-bit & 64-bit), or Mac OS X 10.12 (Sierra),10.13 (High Sierra) and 10.14 (Mojave)
  • 1.6 GHz processor or higher
  • 2 GB RAM for 64-bit (1 GB for 32-bit)
  • 1 GB space available on the harddrive
  • 1024x768 or higher screen resolution
  • Microsoft Office 2013 (32-bit only), Office 2016 (32-bit and 64-bit) and Office 2019.

License options

  • Single user (named user)
  • Site licenses

Academic, Government and Commercial editions available Please call for an offer today!


Here is our collection of resources for learning and getting the most of your purchase of ChemOffice suite.


ChemOffice 18 suite of products - Comparison matrix

    ChemDraw ChemDraw ChemOffice
New features Plaform Prime Professional Professional
Search into Reaxys Win/Mac   X X
ChemACX Explorer Win/Mac     X
Shared HELM Libraries Win/Mac     X


    ChemDraw ChemDraw ChemOffice
Recent Additions Plaform Prime Professional Professional
Hotkey Enhancements Win/Mac X X X
High-Resolution Monitor Support Win/Mac X X X
Facilitated Copy/Pasting Win/Mac X X X
Stereochemistry Handling Improvements Win/Mac X X X
Support for HELM Notation Win/Mac   X X
CAS RN to Structure from Win/Mac   X X
IUPAC name-based Atom Numbering Win/Mac   X X
PerkinElmer SignalsTM Notebook for ChemDraw Win/Mac*     X
Mnova ChemDraw Edition Win/Mac     X
ChemDraw Add-ins Win/Mac     X
ChemDraw JS (with Site Subscription Only) Win/Mac     X
    ChemDraw ChemDraw ChemOffice
Includes Plaform Prime Professional Professional
ChemDraw Win/Mac X X X
Multiple ChemDraw Items Folders Win/Mac X X X
Save and Read Graphic Files Win/Mac X X X
Save and Read Chemical Files Win/Mac X X X
Printing Options Win/Mac X X X
Chemical Templates Win/Mac X X X
Equipment Templates Win/Mac X X X
Analyze/Check Structures Win/Mac X X X
Insert OLE Object in ChemDraw Win X X X
In-place OLE Editing of ChemDraw Objects Win X X X
Show Stereochemistry Win/Mac X X X
Relative Stereochemistry (ISIS compatibility) Win/Mac X X X
Reaction Interpretation Win/Mac X X X
Reaction Mapping Win/Mac X X X
Calculate Properties Win/Mac X X X
Document Tagging Win/Mac X X X
    ChemDraw ChemDraw ChemOffice
Includes Plaform Prime Professional Professional
Manual spectrum/structure assignments Win/Mac X X X
Chemical Polymer Tools Win/Mac X X X
Structure Clean Up Win/Mac X X X
Hotkeys Win/Mac X X X
Expand/Contract Labels Win/Mac X X X
Create/Use Nicknames Win/Mac X X X
Expand Generic Structure Win/Mac X X X
Multicenter Attachments Win/Mac X X X
TLC/GEP Tools Win/Mac X X X
Fragmentation Tools Win/Mac X X X
ChemDraw Active X Plugin Win X X X
Copy/Paste as SMILES Win/Mac X X X
Copy/Paste as SYBYL (SLN) Win/Mac X X X
Copy/Paste as InChI Win/Mac X X X
Copy/Paste as Molfile/Mol3000 Win/Mac X X X
Copy/Paste as CDXML Win/Mac X X X
pKa LogP LogS Win/Mac   X X
Advanced Retrosynthesis Tool Win/Mac   X X
Auto-numbering of multiple structures Win/Mac   X X
tPSA Win/Mac   X X
Search SciFinder Win/Mac   X X
Name = Structure/Structure = Name Win/Mac   X X
cLogP Win/Mac   X X
Biopolymer Toolbar Win/Mac   X X
BioDraw Win/Mac   X X
Reaction Stoichiometry Grid Win/Mac   X X
Calculate 1H 13C NMR Spectra Win/Mac   X X
Query Features Win/Mac   X X
Query Tools Win/Mac   X X
Advanced Stereochemistry Win/Mac   X X
Paste as HELM Win/Mac   X X
Create Sequence Win/Mac   X X
Create New Monomer Win/Mac   X X
Copy as HELM Win/Mac   X X
ChemDraw Cloud Win/Mac*   X X
ChemFinder (Std in CD Prof; Ultra in CO) Win   X X
ChemDraw for Excel Win   X X
Name=Struct for ChemDraw for Excel Win   X X
ChemScript + Python Win   X X

*Access to ChemDraw Cloud and Signals Notebook is provided for one year and can be renewed if current with maintenance.

    ChemDraw ChemDraw ChemOffice
Includes Plaform Prime Professional Professional
CombiChem for Excel Win   X X
3D Search Win   X X
Chem3D (Pro in CDPro; Ultra in CO) Win   X X
Chem3D Hotlink Win   X X
Chem3D Active X Plugin Win   X X
GAMESS Win     X
Interface to MOPAC 2016 Win     X
Interface to Gaussian Win     X
Interface to Conflex Win     X
Interface to Autodock Win     X
ChemFinder / Oracle Win     X
ChemFinder for Office Win     X
BioViz in ChemFinder Ultra Win     X
Compound Profiles in ChemFinder Ultra Win     X
Clustering in ChemFinder Ultra Win     X
Combine ChemFinder Query Hit Lists Win     X
ChemFinder exports to MS Word / Excel Win     X



We provide technical support for all our customers of SigmaPlot. Send an email to This email address is being protected from spambots. You need JavaScript enabled to view it.. When contacting our support department please describe your problem as detailed as possible. Remember to always inform about the productversion and what operating system you are using (platform and version). We also recommend these online support pages and resources:


Here’s what’s new in ChemDraw 18

  • ChemDraw/Reaxys Integration: PerkinElmer and Elsevier® established a partnership to provide you with new and unique ways to improve your Research productivity. It is now possible to draw a molecule or a reaction in ChemDraw,and initiate a structure search into Reaxys. But that’s not all! As part of this partnership, you can also choose to use ChemDraw JS as a drawing editor when you use the online Reaxys website. *requires a Reaxys license* (ChemDraw Professional and above)
  • ChemACX Explorer: Thanks to the new add-in architecture in ChemDraw, you can now explore chemical properties or supplier information for a given molecule by looking up and retrieving information directly from, PerkinElmer’s database of over 10M commercially available compounds, and quickly paste structures back into the canvas. This feature is also available through Signals Notebook Individual Edition. (ChemOffice Professional and above)
  • Shared libraries of monomers: If you are into HELM notation (for peptides, nucleic acids, ADCs etc.) now you can connect to different libraries of monomers, and manage and curate the content of those libraries. One of the default libraries available (“PerkinElmer”) is the public library from (ChemOffice Professional)
  • A unique installer: we have been taking active steps to simplify the activation process of ChemDraw and ChemOffice. One of them is to simplify the number of installers available, therefore no matter which level of ChemDraw you are using, you will download only one installer for ChemDraw Prime, ChemDraw Professional, and ChemOffice Professional. Your license key will determine which applications get installed

Features to try from Release 17.1:

  • Smart Copy/Pasting: You can now paste text-based chemical structure formats like SMILES, Mol, InChI, and HELM as a structure directly using the Edit>Paste (Ctrl/Cmd+V) command, with plain text in the clipboard (Activate the text tool if you need to paste it as text) (ChemDraw Prime and above)
  • IUPAC name-based Atom numbering: Calling the Name-to-Structure or Structure-to-Name function now displays the atom number as they are labeled in the IUPAC name. This feature can be turned on or off in the Preferences. (ChemDraw Professional and above)
  • ChemACX Structure from CAS Registry Number: A new function has been added to look up a CAS RN through, PerkinElmer’s database of commercially available compounds (over 10M substances and 800k CAS RNs provided by vendors) and return the corresponding chemical structure. (ChemDraw Professional and above)


Upcoming training courses and events for ChemDraw and ChemOffice.